官网链接
折扣/货期| 货号：43927-1 mg | 规格：1 mg | 目录价：￥375 |
| 货号：43927-10 mg | 规格：10 mg | 目录价：￥2037 |
| 货号：43927-25 mg | 规格：25 mg | 目录价：￥3229 |
| 货号：43927-5 mg | 规格：5 mg | 目录价：￥1554 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Adavivint
别名:
Lorecivivint|SM-04690
产品描述:
An inhibitor of Wnt signaling (EC50 = 19.5 nM in a reporter assay using SW480 cells); inhibits CMGC family kinases, including Clk2 and DYRK1A (IC50s = 7.8 and 26.9 nM, respectively), as well as Clk1, Clk3, Clk4, DYRK1B, GSK3β, and HIPK1-3 (IC50s = 16.8-239 nM); induces activation of YAP in a reporter assay using HEK293A cells (EC50 = 1.2 nM); induces chondrogenesis in primary human bone marrow-derived MSCs; inhibits pseudorabies virus replication in infected HeLa, BHK-21, Vero, and PK(15) cells (IC50s = 0.16, 0.19, 0.22, and 0.35 µM, respectively); intra-arterial administration decreases disease severity in a surgically induced rat model of osteoarthritis at 0.3 µg/animal; inhibits tumor growth in a patient-derived organoid xenograft mouse model of colorectal cancer at 50 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
505.557403
产品形式:
A solid
纯度:
≥98%
CAS号:
1467093-03-3
分子式:
C29H24FN7O
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