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折扣/货期| 货号：17987-1 mg | 规格：1 mg | 目录价：￥844 |
| 货号：17987-10 mg | 规格：10 mg | 目录价：￥6445 |
| 货号：17987-25 mg | 规格：25 mg | 目录价：￥14110 |
| 货号：17987-5 mg | 规格：5 mg | 目录价：￥3672 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
ADX-47273
产品描述:
A positive allosteric modulator of mGluR5 (EC50s = 0.17 and 0.23 μM for potentiation of glutamate activity in HEK293 cells expressing rat mGluR5 and primary astrocyte cultures, respectively); selective for mGluR5 over rat mGluR1 and human mGluR1 and mGluR4 at 10 μM; decreases the conditioned avoidance response, apomorphine-induced climbing, as well as PCP-, apomorphine-, and amphetamine-induced locomotor activity in rats in a dose-dependent manner; improves recall in a novel object recognition test and reduces impulsivity in the 5CSRTT from 0.1-50 mg/kg; enhances reversal learning in mice in the Morris water maze test
保存温度:
-20
运输温度:
-20
预期分子量:
369.4
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
851881-60-2
分子式:
C20H17F2N3O2
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