深圳欣博盛生物科技有限公司 a1

AGN 193109 (sodium salt)
货号:23975-1 mg 规格:1 mg 目录价:¥3390
货号:23975-500 µg 规格:500 µg 目录价:¥1796
产品详情
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产品名称:
AGN 193109 (sodium salt)
别名:
CD3106
产品描述:
A pan-RAR antagonist (Kd = 2, 2, and 3 nM for RARα, β, and γ, respectively); selective for RARs over RXRs (Kd = >10,000 nM for human RXRα, β, and γ receptors); reverses TTNPB-induced changes in cell morphology in ECE16-1 cells; reverses the growth suppressive effects of all-trans-RA, 13-cis-RA, and 9-cis-RA in ECE16-1 cells when used at a 10-fold molar excess; decreases expression of cytokeratin K5-8, 13, 14, 16, 17, and 19 genes, markers of retinoid action in ECE16-1 cells, when co-administered with TTNPB, but not when used alone; induces cleft palate or frontonasal dysplasia and eye malformations in fetuses of pregnant mice following a single oral dose of 1 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
414.5
产品形式:
A solid
纯度:
≥98%
CAS号:
2319838-82-7
分子式:
C28H23O2 • Na
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