AKT Antibody-单抗-深圳欣博盛生物科技有限公司

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AKT Antibody

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：F53789-0.1ML

规格：0.1 ml

目录价：￥6344

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

AKT Antibody

产品描述:

AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis. This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates. Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported. AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface.
AKT plays a role as key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Signals downstream of phosphatidylinositol 3-kinase (PI(3)K) to mediate the effects of various growth factors such as platelet-derived growth factor (PDGF), epidermal growth factor (EGF), insulin and insulin-like growth factor I (IGF-I). AKT mediates the antiapoptotic effects of IGF-I.

反应种属:

Human

宿主来源:

Mouse

实验应用:

WB, ELISA

同种型:

Mouse IgG1

免疫原:

This AKT antibody was produced from mice immunized with a KLH conjugated synthetic peptide selected from the 430-460 region of human AKT1.

克隆性:

Monoclonal (mouse origin)