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折扣/货期| 货号：16735-1 mg | 规格：1 mg | 目录价：￥1595 |
| 货号：16735-10 mg | 规格：10 mg | 目录价：￥11939 |
| 货号：16735-25 mg | 规格：25 mg | 目录价：￥23879 |
| 货号：16735-5 mg | 规格：5 mg | 目录价：￥6767 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
AL 8810
产品描述:
AL 8810 is an 11β-fluoro analog of PGF2α which acts as a potent and selective antagonist at the FP receptor.{7398} AL 8810 has weak intrinsic agonist activity on FP receptor preparations in the 200-300 nM range, yet it fully antagonizes the activity of the potent FP receptor agonist fluprostenol at this concentration, with EC50 values of approximately 430 nM. AL 8810 fully antagonized the bimatoprost-induced calcium mobilization in Swiss 3T3 fibroblasts at 100 µM, indicating that bimatoprost acts as an FP agonist in this preparation.{9581} The Ki for the inhibition of several potent agonists at the cloned human ciliary body FP receptor is in the range of 1-2 µM.{10426}
保存温度:
-20
运输温度:
-20
预期分子量:
402.5
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
246246-19-5
分子式:
C24H31O4F
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