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折扣/货期| 货号：21378 | 规格：1 mg | 目录价：￥5882.6 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
all-trans-4-hydroxy Retinoic Acid
别名:
4-hydroxy atRA|4-hydroxy RA
产品描述:
A metabolite of all-trans retinoic acid; formed through metabolism of all-trans retinoic acid by CYP26A1, B1, and C1; binds to RARs with a lower affinity than other all-trans retinoic acid metabolites (IC50s = 606, 298, and 892 nM for RARα, RARβ, and RARγ, respectively, in a radioligand binding assay); transactivates RARs with a lower efficacy than other metabolites (EC50s = 791, 64, and 94 nM for RARα, RARβ, and RARγ, respectively) but induces transcription of a reporter plasmid equipotently; inhibits cell growth, halts the cell cycle in the G1 phase, and induces differentiation of NB4 acute promyelocytic leukemia cells (EC50 = 79.8 nM)
保存温度:
-80
运输温度:
-80
预期分子量:
316.4
产品形式:
A solid
纯度:
≥90%
CAS号:
66592-72-1
分子式:
C20H28O3
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