官网链接
折扣/货期| 货号：45326-10 mg | 规格：10 mg | 目录价：￥3832 |
| 货号：45326-25 mg | 规格：25 mg | 目录价：￥7986 |
| 货号：45326-5 mg | 规格：5 mg | 目录价：￥2131 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Almonertinib
别名:
Aumolertinib|HS-10296
产品描述:
An inhibitor of mutant and wild-type EGFR (IC50s = 0.18 and 2.6 nM for EGFRL858R/T790M and wild-type EGFR, respectively, in a cell-free assay); selective for mutant EGFRD761Y, EGFRL747S, and EGFRL861Q (IC50s = 0.84-1.07 nM) over EGFR containing mutations at the G719 residue, EGFRG719C, EGFRG719D, and EGFRG719S (IC50s = 17.25-82.8 nM); decreases proliferation and induces apoptosis in patient-derived NSCLC cells that express EGFR containing exon 20 insertion mutation H773-V774insNPH at 100 nM; reduces tumor growth in an H1975 NSCLC mouse xenograft model and a PDX mouse model of NSCLC
保存温度:
-20
运输温度:
-20
预期分子量:
525.657
产品形式:
A solid
纯度:
≥98%
CAS号:
1899921-05-1
分子式:
C30H35N7O2
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