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折扣/货期| 货号：46377-1 mg | 规格：1 mg | 目录价：￥1005 |
| 货号：46377-10 mg | 规格：10 mg | 目录价：￥7035 |
| 货号：46377-25 mg | 规格：25 mg | 目录价：￥10050 |
| 货号：46377-5 mg | 规格：5 mg | 目录价：￥4529 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Alogabat
别名:
RG-7816|RO7017773
产品描述:
A positive allosteric modulator of the GABAA receptor; potentiates GABA-stimulated currents in X. laevis oocytes expressing α5β3γ2 and α5β3γ3 subunit-containing GABAARs (EC50s = 12 and 20 nM, respectively); selective for α5β3γ2 subunit-containing GABAARs over α1β3γ2, α2β3γ2, and α3β3γ2 subunit-containing GABAARs (Kis = 10.9, 415.8, 178.3, and 113 nM, respectively); >917-fold selective over a panel of 56 receptors, ion channels, and enzymes at 10 µM; reduces repetitive self-grooming behavior in a BTBR mouse model; has antiseizure activity in rats
保存温度:
-20
运输温度:
-20
预期分子量:
409.446
产品形式:
A solid
纯度:
≥98%
CAS号:
2230009-48-8
分子式:
C21H23N5O4
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