| 货号:25275-1 mg | 规格:1 mg | 目录价:¥925 |
| 货号:25275-10 mg | 规格:10 mg | 目录价:¥7035 |
| 货号:25275-5 mg | 规格:5 mg | 目录价:¥3980 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
ALW-II-41-27
产品描述:
A multi-kinase inhibitor; inhibits EphB2, EphA3, Kit, FMS, VEGFR2/KDR, FLT1, FGR, Src, Lyn, BMX, and Bcr-Abl in tyrosine kinase-transformed Ba/F3 cells (EC50s = 50s = 51 and 14 nM, respectively); inhibits wild-type and mutant RET kinases (IC50s = 24.7, 94.2, and 15.8 nM for wild-type, RETV804L, and RETV804M, respectively); reduces growth of NCI-H2286 and HCC-366 cancer cells (GI50s = 0.51 and 0.65 μM, respectively) and RAT1 cells transformed by RETC634R or RETM918T (IC50s = 44 and 56 nM, respectively); inhibits tumor growth in vivo in a mouse PDX model of EphA2-overexpressing TNBC
保存温度:
-20
运输温度:
-20
预期分子量:
607.690189
产品形式:
A crystalline solid
纯度:
≥95%
CAS号:
1186206-79-0
分子式:
C32H32F3N5O2S
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