| 货号:41226-10 mg | 规格:10 mg | 目录价:¥2921 |
| 货号:41226-25 mg | 规格:25 mg | 目录价:¥6097 |
| 货号:41226-5 mg | 规格:5 mg | 目录价:¥1621 |
| 货号:41226-50 mg | 规格:50 mg | 目录价:¥8924 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
AMG 1
别名:
KIN001-237|KIN237|RON Inhibitor 1|RON-IN-1|SYN1143
产品描述:
A c-Met and Ron inhibitor (IC50s = 4 and 9 nM, respectively); selective for c-Met and Ron over seven tyrosine and serine/threonine kinases (IC50s = 160 to 1,900 nM); decreases the levels of phosphorylated MET, ERK1/2, and Akt in HT-29 and BxPC-3 cancer cells, as well as reduces migration in a wound-healing assay using NIH3T3/TPR-Met fibroblasts, in a concentration-dependent manner; reduces tumor volume in a U87 glioma mouse xenograft model at 30 mg/kg twice per day; increases bone volume and bone regrowth area in a mouse model of calvarial defect at 50 µg in an absorbable collagen sponge
保存温度:
-20
运输温度:
-20
预期分子量:
556.584323
产品形式:
A solid
纯度:
≥98%
CAS号:
913376-84-8
分子式:
C31H29FN4O5
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