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折扣/货期| 货号：43488-1 mg | 规格：1 mg | 目录价：￥1018 |
| 货号：43488-10 mg | 规格：10 mg | 目录价：￥5601 |
| 货号：43488-25 mg | 规格：25 mg | 目录价：￥12730 |
| 货号：43488-5 mg | 规格：5 mg | 目录价：￥3819 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
AMG 18 (hydrochloride)
别名:
Kinase-inhibiting RNase Attenuator 8|KIRA8
产品描述:
An IRE1α inhibitor (IC50 = 0.013 µM); selective for IRE1α over JNK3 (IC50 = 2.5 µM) and a panel of 100 kinases at 1 µM; inhibits thapsigargin-induced splicing of XBP1 in a reporter assay using HT-1080 cells; sensitizes 9591PPT and 53631PPT mouse PDAC cells to radiation at 2.5 or 5 µM; reverses increases in fibronectin levels in RSV-infected primary human small airway epithelial cells at 10 µM; decreases blood glucose levels, liver triglyceride and cholesterol levels, and plasma ALT and AST levels in a mouse model of NASH induced by an MCD diet at 50 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
601.122
产品形式:
A solid
纯度:
≥98%
分子式:
C31H29ClN6O3S • XHCl
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