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折扣/货期| 货号：25339-10 mg | 规格：10 mg | 目录价：￥3055 |
| 货号：25339-25 mg | 规格：25 mg | 目录价：￥7102 |
| 货号：25339-5 mg | 规格：5 mg | 目录价：￥1796 |
| 货号：25339-50 mg | 规格：50 mg | 目录价：￥13320 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
AMG 47a
产品描述:
A multi-kinase inhibitor; inhibits Lck, VEGFR2/KDR, p38α, and JAK3 (IC50s = 0.2, 1, 3, and 72 nM, respectively); selective for these kinases over a panel of additional kinases including SYK, JNK1, and PKAβ (IC50s = 292 to >25,000 nM) but does inhibit Src (IC50 = 2 nM); inhibits T cell proliferation in vitro in a mixed lymphocyte reaction assay (IC50 = 30 nM); decreases production of IL-2 induced by an anti-CD3 antibody in mice at 10, 30, and 100 mg/kg; decreases levels of mutant oncogene KRASG12V in HeLa cells in a reporter assay at 1 µM
保存温度:
-20
运输温度:
-20
预期分子量:
535.560329
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
882663-88-9
分子式:
C29H28F3N5O2
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