| 货号:28779-10 mg | 规格:10 mg | 目录价:¥1889 |
| 货号:28779-25 mg | 规格:25 mg | 目录价:¥4194 |
| 货号:28779-5 mg | 规格:5 mg | 目录价:¥1072 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
AMN082
产品描述:
An allosteric mGluR7 agonist; inhibits forskolin-induced cAMP accumulation in CHO cells expressing human mGluR7b (EC50 = 64 nM); selective for mGluR7a and mGluR7b over mGluR1b, mGluR4, and mGluR8a with 140, 90, 15, 18, and 20% activation, respectively, as well as over mGluR2, mGluR3, mGluR5a, mGluR6, GluR3, and NMDA receptors containing NR1a, NR2A, or NR2B subunits at 10 μM; binds to NET and α1-AR; increases the proliferation NPCs and induces their differentiation into neurons at 1 μM; inhibits apomorphine-induced circling in a 6-OHDA-induced PD rat model at 2.5 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
392.5354
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
97075-46-2
分子式:
C28H28N2 • 2HCl
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