深圳欣博盛生物科技有限公司 a1

Anagliptin
货号:36188-1 mg 规格:1 mg 目录价:¥657
货号:36188-10 mg 规格:10 mg 目录价:¥5186
货号:36188-25 mg 规格:25 mg 目录价:¥9688
货号:36188-5 mg 规格:5 mg 目录价:¥2760
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Anagliptin
产品描述:
A DPP-4 inhibitor (IC50 = 3.8 nM); selective for DPP-4 over DPP-8 and DPP-9 (IC50s = 68 and 60 nM, respectively); dietary administration decreases plasma DPP-4 activity, increases plasma GLP-1 levels, suppresses food intake and body weight gain, ameliorates insulin resistance, and improves glucose tolerance in wild-type and glucokinase knockout mouse models of high-fat diet-induced diabetes at 0.05 and 0.3% w/w; decreases hepatic lipid and M1 macrophage accumulation and prevents hepatic fibrosis and steatohepatitis in mice fed a high-cholesterol high-fat diet or a CDAHF diet; reduces atherosclerotic lesion size in an Apoe-/- mouse model of atherosclerosis
保存温度:
-20
运输温度:
-20
预期分子量:
383.5
产品形式:
A solid
纯度:
≥95%
CAS号:
739366-20-2
分子式:
C19H25N7O2
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