| 货号:RQ5317 | 规格:100 ul | 目录价:¥6488.05 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Androgen Receptor Antibody
产品描述:
The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (SBMA, also known as Kennedy's disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Alternative splicing results in multiple transcript variants encoding different isoforms. [RefSeq]
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
同种型:
Rabbit IgG
免疫原:
A synthetic peptide specific to human Androgen Receptor was used as the immunogen for the Androgen Receptor antibody.
克隆性:
Rabbit Monoclonal
克隆号:
HD-1
纯化方式:
Affinity purified
保存温度:
Store the Androgen Receptor antibody at -20oC.
产品形式:
Purified
存储溶液:
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA
产地:
美国
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