Animal-Free Recombinant Human sRANK Ligand (E.coli derived)-无动物成分蛋白-深圳欣博盛生物科技有限公司

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Animal-Free Recombinant Human sRANK Ligand (E.coli derived)

品牌：PeproTech

官网链接

说明书

折扣/货期

货号：AF-310-01-100UG	规格：100 ug	目录价：￥26243
货号：AF-310-01-10UG	规格：10 ug	目录价：￥3369
货号：AF-310-01-1MG	规格：1 mg	目录价：￥101270
货号：AF-310-01-250UG	规格：250 ug	目录价：￥44224
货号：AF-310-01-2UG	规格：2 ug	目录价：￥1498
货号：AF-310-01-500UG	规格：500 ug	目录价：￥65697
货号：AF-310-01-50UG	规格：50 ug	目录价：￥15759

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Animal-Free Recombinant Human sRANK Ligand (E.coli derived)

别名:

soluble Receptor Activator of NF-kappaB Ligand, TNFSF11, TRANCE (TNF-related activation-induced cytokine), OPGL, ODF (Osteoclast differentiation factor)

产品描述:

RANKL and RANK are members of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. RANK (receptor) was originally identified as a dendritic cell-membrane protein, which, by interacting with RANKL, augments the ability of dendritic cells. These dendritic cells then stimulate naive T-cell proliferation in a mixed lymphocyte reaction, promote the survival of RANK+ T-cells, and regulate T-cell-dependent immune response. RANKL, which is expressed in a variety of cells, including osteoblasts, fibroblasts, activated T-cells and bone marrow stromal cells, is also capable of interacting with a decoy receptor called OPG. Binding of soluble OPG to sRANKL inhibits osteoclastogenesis by interrupting the signaling between stromal cells and osteoclastic progenitor cells, thereby leading to excess accumulation of bone and cartilage. Human RANKL is reactive on murine cells. Recombinant Human sRANK Ligand is a 20.0 kDa polypeptide comprising the TNF-homologous region of RANKL (176 amino acid residues).

宿主来源:

E.coli

保存温度:

Minus 20C

运输温度:

Room Temperature

产品形式:

Bulk

产地:

美国

生产商:

PeproTech