| 货号:AF-210-21-100UG | 规格:100 ug | 目录价:¥26079 |
| 货号:AF-210-21-10UG | 规格:10 ug | 目录价:¥3358 |
| 货号:AF-210-21-1MG | 规格:1 mg | 目录价:¥100778 |
| 货号:AF-210-21-250UG | 规格:250 ug | 目录价:¥44010 |
| 货号:AF-210-21-2UG | 规格:2 ug | 目录价:¥1493 |
| 货号:AF-210-21-500UG | 规格:500 ug | 目录价:¥65377 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Animal-Free Recombinant Murine IL-21
别名:
Interleukin-21, Za11
产品描述:
IL-21 is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. Its action generally enhances antigen-specific responses of immune cells. The biological effects of IL-21 include: inducing the differentiation of T cell-stimulated B cells into plasma cells and memory B cells; the stimulation of IgG production in conjunction with IL-4; and the induction of apoptotic effects in naive B cells and stimulated B cells in the absence of T-cell signaling. Additionally, IL-21 promotes the anti-tumor activity of CD8+ T cells and NK cells. IL-21 exerts its effect through binding to a specific type I cytokine receptor, IL-21R, which also contains the gamma chain (gammac) found in other cytokine receptors, including IL-2, IL-4, IL-7, IL-9 and IL-15. The IL-21/IL-21R interaction triggers a cascade of events, which includes activation of the tyrosine kinases JAK1 and JAK3, followed by activation of the transcription factors STAT1 and STAT3. Recombinant Murine IL-21 is a 15.0 kDa protein consisting of 130 amino acid residues.
宿主来源:
E.coli
保存温度:
Minus 20C
运输温度:
Room Temperature
产品形式:
Bulk
产地:
美国
生产商:
PeproTech
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