Annexin A1 Antibody-多抗-深圳欣博盛生物科技有限公司

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Annexin A1 Antibody

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：R31548

规格：100 ug

目录价：￥6488.05

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Annexin A1 Antibody

产品描述:

ANXA1, also known as Lipocortin I or Annexin A1, is a protein that in humans is encoded by the ANXA1 gene. It is mapped to 9q21.13. It belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. ANXA1 protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Lower peptide concentrations possibly found in inflammatory situations elicit Ca(2+) transients without fully activating the mitogen-activated protein kinase pathway. This causes a specific inhibition of the transendothelial migration of neutrophils and a desensitization of neutrophils toward a chemoattractant challenge. These findings identified ANXA1 peptides as novel, endogenous FPR ligands and established a mechanistic basis of ANXA1-mediated antiinflammatory effects.

反应种属:

Human, Monkey, Rat

宿主来源:

Rabbit

实验应用:

WB, IHC-P

同种型:

Rabbit IgG

免疫原:

Human partial recombinant protein (AA 2-346) was used as the immunogen for this Annexin A1 antibody.

克隆性:

Polyclonal (rabbit origin)

纯化方式:

Antigen affinity

保存温度:

After reconstitution, the Annexin A1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

产品形式:

Antigen affinity purified

存储溶液:

0.5mg/ml if reconstituted with 0.2ml sterile DI water

产地:

美国

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