anti-B7-H4 (human), Rabbit Monoclonal (RM525)-单抗-深圳欣博盛生物科技有限公司

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anti-B7-H4 (human), Rabbit Monoclonal (RM525)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：REV-31-1418-00-R100

规格：100 ul

目录价：￥5726

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-B7-H4 (human), Rabbit Monoclonal (RM525)

别名:

B7 homolog 4; V-set Domain-containing T Cell Activation Inhibitor 1; VTCN1; B7h.5; Immune Costimulatory Protein B7-H4; T Cell Costimulatory Molecule B7x; Protein B7S1

产品描述:

B7-H4 is a B7 family member that negatively regulates T cell immunity by inhibiting of T cell proliferation, cytokine production, and cell cycle progression. In vitro, B7-H4 inhibits CD4+ and CD8+ T cell proliferation, cytokine production, and generation of alloreactive cytotoxic T-cells (CTLs). In vivo, blockade of endogenous B7-H4 by specific monoclonal antibody promotes T cell responses. B7-H4 ia an important negative regulator of innate immunity through growth inhibition of neutrophils. B7-H4 is expressed on some tumor cancer cells. The role of B7-H4 in tumor progression may be to transform precancerous cells and then protect them from immunosurveillance.

宿主来源:

Rabbit

实验应用:

IHC, WB

靶标/特异性:

This antibody reacts to the human B7-H4 protein.

同种型:

Rabbit IgG

免疫原:

A peptide corresponding to the internal region of human B7H4.

克隆号:

RM525