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折扣/货期| 货号：AG-20T-0139-C100 | 规格：100 ug | 目录价：￥3840 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-Caspase-11 (mouse), mAb (8A5)
别名:
Caspase-11 (mouse); Protease ICH-3 (mouse)
产品描述:
Caspase-11 not only activates caspase-1, that is required for the maturation of proinflammatory cytokines such as interleukin-1 (IL-1) and interleukin-18 (IL-18), but also activates caspase-3, leading to cellular apoptosis under pathological conditions. In most cells, caspase-11 is only expressed upon induction with pro-inflammatory stimuli. Caspase-11 is an essential mediator of endotoxic shock and caspase-11-deficient mice are resistant to endotoxic shock. LPS-induced caspase-11 regulates lymphocyte apoptosis by activating both caspase-3 and caspase-7.
实验应用:
ELISA, FACS, IP, WB
靶标/特异性:
Recognizes mouse and rat full-length caspase-11 protein. Detects two bands of ~38kDa and ~43kDa by Western blot.
同种型:
Rat IgG1kappa
免疫原:
Recombinant mouse caspase-11 (p20 fragment).
克隆号:
8A5
产品浓度:
1mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 0.02% sodium azide.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
内毒素水平:
<0.1EU/µg purified protein (LAL test; Lonza).
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