anti-Caspase-11 (mouse), mAb (8A5)-单抗-深圳欣博盛生物科技有限公司

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anti-Caspase-11 (mouse), mAb (8A5)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-20T-0139-C100

规格：100 ug

目录价：￥3840

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-Caspase-11 (mouse), mAb (8A5)

别名:

Caspase-11 (mouse); Protease ICH-3 (mouse)

产品描述:

Caspase-11 not only activates caspase-1, that is required for the maturation of proinflammatory cytokines such as interleukin-1 (IL-1) and interleukin-18 (IL-18), but also activates caspase-3, leading to cellular apoptosis under pathological conditions. In most cells, caspase-11 is only expressed upon induction with pro-inflammatory stimuli. Caspase-11 is an essential mediator of endotoxic shock and caspase-11-deficient mice are resistant to endotoxic shock. LPS-induced caspase-11 regulates lymphocyte apoptosis by activating both caspase-3 and caspase-7.

实验应用:

ELISA, FACS, IP, WB

靶标/特异性:

Recognizes mouse and rat full-length caspase-11 protein. Detects two bands of ~38kDa and ~43kDa by Western blot.

同种型:

Rat IgG1kappa

免疫原:

Recombinant mouse caspase-11 (p20 fragment).

克隆号:

8A5

产品浓度:

1mg/ml