anti-Caspase-12 (mouse), mAb (12G6)-单抗-深圳欣博盛生物科技有限公司

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anti-Caspase-12 (mouse), mAb (12G6)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-20T-0141-C100

规格：100 ug

目录价：￥3480

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-Caspase-12 (mouse), mAb (12G6)

别名:

CASP-12

产品描述:

Caspase-12 is a member of the ICE/CED-3 family of caspases and is detected as a protein of ~51kDa. Overexpression of caspase-12 in cells induces apoptosis. Capase-12 is localized to the endoplasmatic reticulum (ER) and activated by ER stress and specifically cleaves and activates pro-caspase-9 and is also thought to be involved in the apoptosis induced by viral infection. Caspase-12-deficient mice are resistant to ER stress-induced apoptosis. Caspase-12 is probably expressed in many and perhaps all mouse tissues and is expressed at high levels in skeletal muscle, heart, lung and kidney and at moderate levels in brain and liver. In many humans caspase-12 is a pseudo gene and not expressed.

实验应用:

ELISA, FACS, WB

靶标/特异性:

Recognizes an epitope within the p20 fragment of mouse caspase-12. Detects a band of ~51kDa by Western blot. Does not cross-react with mouse caspase-1 or -11.

同种型:

Rat IgG1kappa

免疫原:

Recombinant mouse caspase-12 (p20 fragment) and synthetic peptide corresponding to aa 183-205 of mouse caspase-12.

克隆号:

12G6

产品浓度:

1mg/ml

保存温度:

+4°C

运输温度:

产品形式: