anti-CD14 (human), Rabbit Monoclonal (RM415)-单抗-深圳欣博盛生物科技有限公司

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anti-CD14 (human), Rabbit Monoclonal (RM415)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：REV-31-1301-00-R100

规格：100 ul

目录价：￥5726

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-CD14 (human), Rabbit Monoclonal (RM415)

别名:

Monocyte Differentiation Antigen CD14

产品描述:

CD14 is a GPI-anchored glycoprotein that is constitutively expressed on the surface of mature monocytes, macrophages and neutrophils and which is part of the innate immune system as a pattern recognition receptor. CD14 serves as a multifunctional lipopolysaccharide receptor together with TLR-4 and MD-2) and is released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 can discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. Further, CD14 has been shown to bind apoptotic cells, and can affect allergic, inflammatory and infectious processes. Diseases associated with CD14 dysfunction include mycobacterium chelonae infection and croup.

宿主来源:

Rabbit

实验应用:

IHC, WB

靶标/特异性:

This antibody reacts to human to CD14.

同种型:

Rabbit IgG

免疫原:

A peptide corresponding to the C-terminus of human CD14.

克隆号:

RM415