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折扣/货期| 货号：REV-31-1303-00-R100 | 规格：100 ul | 目录价：￥5726 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-CD278 (human), Rabbit Monoclonal (RM417)
别名:
ICOS; Inducible T-cell Costimulator; Activation-inducible Lymphocyte Immunomediatory Molecule
产品描述:
CD278 (ICOS; CRP1; CD28-related protein-1) is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. ICOS is expressed on most CD45RO+ cells. ICOS expression is upregulated within approximately 24-48 hours of activation on Th primed cells. B7-H2, a member of the B7 family of costimulatory ligands, has been identified as the ICOS ligand. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation. It is essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. It enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells.
宿主来源:
Rabbit
实验应用:
IHC
靶标/特异性:
This antibody reacts to human CD278.
同种型:
Rabbit IgG
免疫原:
A peptide corresponding to the C-terminus of human CD278.
克隆号:
RM417
产品浓度:
N/A
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产地:
瑞士
纯度:
Protein A purified.
上一个:anti-Cytokeratin-7 (human), Rabbit Monoclonal (RM416)
下一个:anti-CD25 (human), Rabbit Monoclonal (RM418)
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