anti-CD278 (human), Rabbit Monoclonal (RM417)-单抗-深圳欣博盛生物科技有限公司

首页产品中心单抗

anti-CD278 (human), Rabbit Monoclonal (RM417)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：REV-31-1303-00-R100

规格：100 ul

目录价：￥5726

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-CD278 (human), Rabbit Monoclonal (RM417)

别名:

ICOS; Inducible T-cell Costimulator; Activation-inducible Lymphocyte Immunomediatory Molecule

产品描述:

CD278 (ICOS; CRP1; CD28-related protein-1) is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. ICOS is expressed on most CD45RO+ cells. ICOS expression is upregulated within approximately 24-48 hours of activation on Th primed cells. B7-H2, a member of the B7 family of costimulatory ligands, has been identified as the ICOS ligand. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation. It is essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. It enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells.

宿主来源:

Rabbit

实验应用:

IHC

靶标/特异性:

This antibody reacts to human CD278.

同种型:

Rabbit IgG

免疫原:

A peptide corresponding to the C-terminus of human CD278.

克隆号:

RM417