深圳欣博盛生物科技有限公司 a1

anti-CD40 (human), mAb (EA-5)
货号:ANC-300-020 规格:100 ug 目录价:¥3010
产品详情
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产品名称:
anti-CD40 (human), mAb (EA-5)
别名:
CD40L Receptor; CDw40; Tumor Necrosis Factor Receptor Superfamily Member 5; TNFRSF5
产品描述:
CD40 belongs to the TNF-receptor superfamily and is essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development and germinal center formation. The interaction of CD40-CD40L is necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells and macrophages. Consistent with its widespread expression on normal cells, CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.
实验应用:
ELISA, FACS, FUNC
同种型:
Mouse IgG1
免疫原:
Murine L cells transfectants expressing human CD40.
克隆号:
EA-5
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5mg/ml Gentamicin sulfate
产地:
瑞士
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