anti-CD40 (human), mAb (EA-5) (APC)-单抗-深圳欣博盛生物科技有限公司

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anti-CD40 (human), mAb (EA-5) (APC)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：ANC-300-060

规格：120 tests

目录价：￥6706

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-CD40 (human), mAb (EA-5) (APC)

别名:

CD40L Receptor; CDw40; Tumor Necrosis Factor Receptor Superfamily Member 5; TNFRSF5

产品描述:

CD40 belongs to the TNF-receptor superfamily and is essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development and germinal center formation. The interaction of CD40-CD40L is necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells and macrophages. Consistent with its widespread expression on normal cells, CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.

实验应用:

ELISA, FACS

靶标/特异性:

Antibody clone EA-5 recognizes the human CD40 molecule.

同种型:

Mouse IgG1

免疫原:

Murine L cells transfectants expressing human CD40.

克隆号:

EA-5

偶联:

APC