| 货号:AG-20B-0036-C100 | 规格:100 ug | 目录价:¥1800 |
| 货号:AG-20B-0036-C500 | 规格:500 ug | 目录价:¥3240 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
anti-CD40 (mouse), mAb (FGK45)
别名:
Tumor Necrosis Factor Receptor Superfamily Member 5; CD40L Receptor
产品描述:
CD40 belongs to the TNF-receptor superfamily and is essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. The interaction of CD40-CD40L is necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells and macrophages. Consistent with its widespread expression on normal cells, CD40 is also expressed on a wide range of tumor cells, including non-Hodgkin's and Hodgkin's lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.
宿主来源:
Purified from concentrated hybridoma tissue culture supernatant.
实验应用:
FACS, FUNC
靶标/特异性:
Recognizes mouse CD40.
同种型:
Rat IgG2a
免疫原:
Recombinant mouse CD40 fusion protein.
克隆号:
FGK45
产品浓度:
1mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 0.02% sodium azide.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
内毒素水平:
<0.01EU/µg purified protein (LAL test; Lonza).
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