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折扣/货期| 货号：REV-31-1146-00-R100 | 规格：100 ul | 目录价：￥5726 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-CD44 (human), Rabbit Monoclonal (RM264)
别名:
Epican; Extracellular Matrix Receptor III; ECMR-III; GP90 Lymphocyte Homing/Adhesion Receptor; HUTCH-I; Heparan Sulfate Proteoglycan; Hermes Antigen; Hyaluronate Receptor; Phagocytic Glycoprotein 1; PGP-1; Phagocytic Glycoprotein I; PGP-I
产品描述:
CD44 cell surface antigen is a 100 kDa type 1 transmembrane glycoprotein widely expressed on human leucocytes, white matter of the brain and by some epithelial cells of the intestine and breast. Several isoforms of CD44 exist. CD44 is a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, cell adhesion and migration. CD44 also participates in a wide variety of cellular functions including including lymphocyte activation, recirculation and homing, hematopoiesis and tumor metastasis. CD44 function is controlled by its posttranslational modifications. CD44 is expressed by hematopoietic, non-hematopoietic cells and epithelial tissues. Further, bone marrow myeloid cells and memory T cells express CD44 at high levels, and peripheral B and T cells can upregulate the expression of CD44 in response to certain stimulatory events. CD44 expression may be up-regulated upon some carcinomas, and it has been speculated that this may be related to metastatic potential. Diseases associated with CD44 dysfunction include superficial keratitis and lichen sclerosus. CD44 also may be related to tumor metastasis formation.
宿主来源:
Rabbit
实验应用:
IHC, WB
靶标/特异性:
This antibody reacts to the extracellular domain of human CD44.
同种型:
Rabbit IgG
免疫原:
A peptide corresponding to the extracellular domain of human CD44.
克隆号:
RM264
产品浓度:
N/A
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产地:
瑞士
纯度:
Protein A purified.
上一个:anti-Histone H3.3 G34W Mutant (human), Rabbit Monoclonal (RM263) (Biotin)
下一个:anti-PTEN (human), Rabbit Monoclonal (RM265)
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