官网链接
折扣/货期| 货号：ANC-198-040 | 规格：120 tests | 目录价：￥3542 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-CD47 (human), mAb (ANC2F6) (FITC)
别名:
IAP; Integrin Associated Protein; Leukocyte Surface Antigen CD47
产品描述:
Human CD47 (IAP; Integrin Associated Protein) is a broadly expressed Ig superfamily glycoprotein of about 50kD with a long extracellular Ig like domain, 5 transmembrane domains and an alternatively spliced intracellular C-terminal domain. It interacts with its ligand SIRPalpha (CD172a; Signal Regulatory Protein) expressed mainly on myeloid cells serving as a negative immune regulator, inhibiting phagocytosis. The CD47-SIRPalpha axis is being investigated as possible anti-tumor immune intervention point. Blockade of this interaction has shown promise in models of HNSCC, glioma and breast cancer.
宿主来源:
Purified from concentrated hybridoma tissue culture supernatant.
实验应用:
ELISA, FACS
靶标/特异性:
Binds to an epitope within the extracellular Ig-like domain of human CD47.
同种型:
Mouse IgG1kappa
免疫原:
Recombinant human CD47 (extracellular Ig domain).
克隆号:
ANC2F6
偶联:
FITC
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 5% Glycerol, 0.2%BSA, 0.04% sodium azide.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
您可能感兴趣的产品
sPLA2 (human Type XIIA) Monoclonal Antibody (Clone 44)
货号：45742
HLA-DR (human) Immunoaffinity Resin (Clone L243)
货号：44917
Clusterin Monoclonal (Clone 9E2E2)
货号：37066
H2AX Phospho-Ser 139 (1H2) Monoclonal Antibody
货号：G01106.100 µL
TLF (TBP like factor) Monoclonal Antibody
货号：G01105.100 µL
TIF2 Monoclonal Antibody
货号：G01104.100 µL
TIF2 Monoclonal Antibody
货号：G01103.100 µL
TIF1δ(Transcriptional intermediary factor 1d) Monoclonal Antibody
货号：G01102.100 µL
促销活动
精品推荐
相关产品推荐
anti-CD3 (human), mAb (TR66)
货号：AG-20B-0087-C100
anti-CD3 (human), mAb (TR66) (preservative free)
货号：AG-20B-0087PF-C100
anti-PLXDC2, mAb (Bonny-2) (25 ug)
货号：AG-20B-0089-TRIAL
Histone H3.3 Mutation Antibody Panel (G34W, G34R, G34V)
货号：REV-31-1325-MP-KI01
Histone H3 Mutation Antibody Panel (K4M, K9M, K27M, K36M)
货号：REV-31-1326-MP-KI01
Histone H3 Mutation Antibody Panel (K4M, K9M, K27M, K36M) + H3.3 Mutation (G34W, G34R, G34V)
货号：REV-31-1327-MP-KI01
复制QQ号成功，请打开QQ后添加好友进行咨询