anti-CRP (human), mAb (rec.) (SH1177-F3)-单抗-深圳欣博盛生物科技有限公司

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anti-CRP (human), mAb (rec.) (SH1177-F3)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-27B-6320-C050

规格：50 ug

目录价：￥3492

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-CRP (human), mAb (rec.) (SH1177-F3)

别名:

C-reactive Protein; PTX1

产品描述:

C-reactive protein (CRP) is a major cyclic, pentameric acute phase protein compound consisting of five identical, noncovalently bound, nonglycosylated subunits. CRP is produced by the liver, and its plasma levels rise dramatically during inflammatory processes occurring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.), plays an important role in innate immunity and mediates activities associated with pre-immune nonspecific host resistance. Specifically, there is a 100-1000 fold increase of CRP in response to injury, infection or inflammation. CRP is opsonic, an initiator of the classical complement cascade, and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. CRP is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host, and initiates pathogen elimination by interacting with humoral and cellular effector systems in the blood. Patients with elevated basal levels of CRP have been shown to be an increased risk for hypertension and cardiovascular disease.

宿主来源:

Protein A purified from HEK293 cell culture supernatant.

实验应用:

ELISA, WB

靶标/特异性:

Recognizes human C-reactive protein (CRP).

同种型:

Human IgG1

免疫原:

Recombinant human C-reactive protein (CRP).

克隆号:

SH1177-F3