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折扣/货期| 货号：JAI-MBY-020P | 规格：20 ug | 目录价：￥3794 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-Dibromo-tyrosine [DiBrY], mAb (3A5)
产品描述:
Neutrophils and eosinophils play an important role in the defence system against microbial infection. Myeloperoxidase (MPO) and eosinophil peroxidase (EPO) are known to catalyze formation of hypochlorous acid (HOCl) and hypobromous acid (HOBr). These reactive intermediates may react with proteins, lipids and nucleotides, and it has been reported to form tyrosine halogenation such as dibromotyrosine (DiBrY). DiBrY is a Br-modified tyrosine at 3- and 5- position, which is one of the major oxidative products derived from neutrophil myeloperoxidase. DiBrY may be a novel biomarker for tissue damage which is related to inflammatory and allergic disorders.
实验应用:
ELISA, IHC, WB
靶标/特异性:
Recognizes dibromotyrosine (DiBrY), N-acetylated dichloro tyrosine (NAcDiClY), diiodo tyrosine (DiIY), N-bromosuccinimide-treated BSA, HOCl-treated BSA and dibromo-tyrosone conjugated BSA (halogene-modified tyrosine at both 3- and 5-position). Does not cross-react with dityrosine-conjugated BSA, peroxynitrite-treated BSA, tyrosine (Y), chrolotyrosine(ClY), 3-3’-dityrosine (DiY), 3-aminotyrosine (NH2Y), 3-nitrotyrosine (NO2Y), phenylalanine (Phe), o-phosphotyrosine, 3,4-dihydroxyphenylacetic acid (DOPA) and 2-hydroxy-4-phenylacetic acid. Weakly cross-reacts with Bromotyrosine (BrY).
同种型:
Mouse IgG1kappa
免疫原:
Brominated keyhole limpet hemocyanin.
克隆号:
3A5
保存温度:
+4°C
运输温度:
BI
产品形式:
solid
存储溶液:
Lyophilized. Contains 10mM Phosphate buffered saline (pH7.4).
产地:
瑞士
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