anti-FLIP (human), mAb (NF6) (Biotin)-单抗-深圳欣博盛生物科技有限公司

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anti-FLIP (human), mAb (NF6) (Biotin)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-20B-0056B-C050

规格：50 ug

目录价：￥3480

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-FLIP (human), mAb (NF6) (Biotin)

别名:

I-FLICE; CLARP; CASPER; Usurpin, CASH; FLAME-1

产品描述:

FLIP is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells and acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. FLIP lacks enzymatic (caspase) activity. FLIP is highly expressed in skeletal muscle, pancreas, heart, kidney, placenta and peripheral blood leukocytes.

实验应用:

ICC, IHC, WB

靶标/特异性:

Recognizes short (FLIPS) and long (FLIPL) splice variants of human FLIP. This antibody recognizes an epitope in the N-terminal DED region (aa1-194).

同种型:

Mouse IgG1

免疫原:

Recombinant human FLIP (aa 1-480).

克隆号:

NF6

偶联:

Biotin