anti-Helicobacter pylori, Rabbit Monoclonal (RM429)-单抗-深圳欣博盛生物科技有限公司

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anti-Helicobacter pylori, Rabbit Monoclonal (RM429)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：REV-31-1317-00-R100

规格：100 ul

目录价：￥5726

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-Helicobacter pylori, Rabbit Monoclonal (RM429)

别名:

H. Pylori; Campylobacter Pylori

产品描述:

Helicobacter pylori (H. pylori) is a bacterial class-I carcinogen that specifically colonizes the gastric epithelium of humans as a unique niche, where it can induce inflammatory disorders (e.g. ulceration, chronic gastritis, etc.) and malignant neoplastic diseases (mucosa-associated lymphoid tissue [MALT] lymphoma and gastric cancer). To resist the hostile environment in the stomach, H. pylori has developed highly sophisticated mechanisms to establish life-long infections in the stomach if not therapeutically eradicated. Helicobacter pylori can exist in a number of locations: in the mucus; attached to epithelial cells; or inside of vacuoles in epithelial cells, where it produces adhesins that bind to membrane-associated lipids and carbohydrates to help its adhesion to epithelial cells. Helicobacter pylori contains a hydrogenase enzyme and obtains energy by oxidizing molecular hydrogen produced by other intestinal bacteria. It also excretes urease in order to convert urea into ammonia and bicarbonate which neutralizes the acidic environment of the stomach. Helicobacter pylori OMPs (outer membrane proteins) are involved in Helicobacter pylori adhesion and can cause signal transduction events in host cells. HP-NAP acts as a chemoattractant for nrutrophils, which produce oxygen radicals, cytokines and chemokines, crucial in driving the Th1 inflammation in H. pylori infection.

宿主来源:

Rabbit

实验应用:

IHC

靶标/特异性:

RM429 reacts to Helicobacter pylori.

同种型:

Rabbit IgG

免疫原:

Proteins purified from Helicobacter pylori.

克隆号:

RM429