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折扣/货期| 货号：JAI-MHL-021P | 规格：20 ug | 目录价：￥2856 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-Hexanoyl-Lys [HEL], mAb (5F12)
产品描述:
Oxidative damage to lipids (lipid peroxidation) has been found to play an important role in various disease and aging processes. During early stages of lipid peroxidation, lipid hydroperoxides (LOOH) are formed. These can react additionally to form later stage end products such as malondialdehyde (MDA) and hydroxynonenal (HNE). LOOH is measured to quantify early stage or acute lipid peroxidation while MDA is commonly measured to quantify late stage or chronic lipid peroxidation. More recently, it has been reported that 13-hydroperoxyoctadecanoic acid (13-HPODE), a precursor to 13-hydroxyoctadecanoic acid (13-HODE) can react with proteins to form measurable adducts by covalently binding to specific amino acid residues. The Hexanoyl-Lysine (HEL) adduct is formed upon oxidative modification of omega-6 fatty acids such as linoleic acid, the predominant polyunsaturated fatty acid (PUFA) in the human diet, and arachidonic acid. HEL may be another useful biomarker for detecting and quantifying the earlier stages of lipid peroxidation.
实验应用:
ELISA, IHC, WB
靶标/特异性:
Recognizes Hexanoyl-Lys adducts. Does not cross-react with MDA, glyoxal, methylglyoxal, 1-hexanal, 2-hexenal, 1-nonannal, 2-nonenal, 4-hudroxy-2-nonenal.
同种型:
Mouse IgG1kappa
免疫原:
N epsilon hexanoyl-keyhole limpet hemocyanin (HEL-KLH).
克隆号:
5F12
保存温度:
+4°C
运输温度:
BI
产品形式:
solid
存储溶液:
Lyophilized. Contains 10mM PBS (pH7.4), 5% sucrose, 1% BSA and 0.05% Procline 950.
产地:
瑞士
上一个:anti-4-Hydroxy-2-hexenal [4-HHE], mAb (HHE53)
下一个:anti-4-Hydroxy-2-nonenal [4-HNE], mAb (HNEJ-2)
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