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折扣/货期| 货号：REV-31-1415-00-R100 | 规格：100 ul | 目录价：￥5726 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-LSD1+8a (human), Rabbit Monoclonal (RM523)
别名:
Lysine-Specific Demethylase 1 isoform 8a
产品描述:
LSD1+8a (Lysine-Specific Demethylase 1 isoform 8a) is an alternatively spliced variant of the LSD1 (KDM1A) gene that includes the neuron-specific exon 8a. This isoform is predominantly expressed in the brain and plays a key role in neuronal differentiation and function. While canonical LSD1 regulates gene expression by demethylating histone H3 on lysine 4 (H3K4me1/2), the +8a variant shows altered substrate specificity and interacts with different cofactors, contributing to neuron-specific transcriptional programs. Dysregulation of LSD1+8a has been implicated in neurodevelopmental disorders and certain cancers.
宿主来源:
Rabbit
实验应用:
IHC, WB
靶标/特异性:
RM523 reacts to reacts to human LSD1+8a (isoform 8a). This antibody may also react to mouse or rat LSD1+8a, as predicted by immunogen homology.
同种型:
Rabbit IgG
免疫原:
A synthetic peptide with an amino acid sequence corresponding to human LSD1 isoform 8a.
克隆号:
RM523
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产地:
瑞士
纯度:
Protein A purified.
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