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折扣/货期| 货号：AG-20B-0041-C100 | 规格：100 ug | 目录价：￥3480 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-LTbetaR (mouse), mAb (3C8)
别名:
Lymphotoxin-beta Receptor; Tumor Necrosis Factor Receptor 2 Related Protein; Tumor Necrosis Factor C Receptor; Tumor Necrosis Factor Receptor Superfamily Member 3; TNFRSF3
产品描述:
The LTbetaR activates two different NF-kappaB pathways that lead to distinct patterns of gene induction, including selected chemokines and the cytokine BAFF, which is essential for the survival of mature B lymphocytes. LTbetaR activates the classical NF-kappaB (relA/p50) pathway, like the type 1 TNF receptor (TNFR1), that regulates proinflammatory genes, like the chemokine MIP1beta. However, LTbetaR, unlike TNFR1, also activates the processing of p100 to form RelB/p52 complexes, which activate genes involved in lymphoid organ formation and lymphocyte survival.
宿主来源:
Purified from concentrated hybridoma tissue culture supernatant.
实验应用:
FUNC (Blocking)
靶标/特异性:
Recognizes mouse LTbetaR.
同种型:
Rat IgG1kappa
免疫原:
Recombinant mouse LTbetaR (cysteine-rich region/aa 31-221).
克隆号:
3C8
产品浓度:
1mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
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