anti-mTOR (human), Rabbit Monoclonal (RM274)-单抗-深圳欣博盛生物科技有限公司

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anti-mTOR (human), Rabbit Monoclonal (RM274)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：REV-31-1155-00-R100

规格：100 ul

目录价：￥5726

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-mTOR (human), Rabbit Monoclonal (RM274)

别名:

mTOR; MTOR; FRAP; EC=2.7.11.1; Rapamycin Target Protein 1; Mammalian Target of Rapamycin; Rapamycin and FKBP12 target 1; Mechanistic Target of Rapamycin; Serine/Threonine-Protein Kinase mTOR

产品描述:

Mammalian target of rapamycin (mTOR) is a serine/threonine kinase that plays a key role in cell growth, cell proliferation, and protein synthesis. mTOR mediates phosphoinositide 3-kinase and Akt/PKB signaling, resulting in phosphorylation of 4EBP1, and initiation of mRNA translation. A second pathway involves regulation of ribosomal S6 kinase, which affects ribosome biogenesis and translation elongation. mTOR is phosphorylated at Ser2448 via the PI3 kinase/Akt signaling pathway and autophosphorylated at Ser2481. mTOR plays a key role in cell growth and homeostasis and may be abnormally regulated in tumors. Mutations affecting the gene results in Smith-Kingsmore syndrome.

宿主来源:

Rabbit

实验应用:

IHC, WB

靶标/特异性:

This antibody reacts to human serine/threonine-protein kinase mTOR. This antibody may also react to mouse or rat mTOR, as predicted by immunogen homology.

同种型:

Rabbit IgG

免疫原:

A peptide corresponding to human serine/threonine-protein kinase mTOR.

克隆号:

RM274

产品浓度:

N/A

保存温度:

+4°C

运输温度:

产品形式: