| 货号:REV-31-1409-00-R100 | 规格:100 ul | 目录价:¥5726 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
anti-MUC-17 (Mucin-17) (human), Rabbit Monoclonal (RM517)
别名:
Mucin-17; Small Intestinal Mucin-3 (MUC-3)
产品描述:
Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC-17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. MUC-17 interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. MUC-17 probably plays a role in maintaining homeostasis on mucosal surfaces. Increased expression of this molecule has been reported in colon cancer.
宿主来源:
Rabbit
实验应用:
IHC
靶标/特异性:
This antibody reacts to human Muc-17 (Mucin-17).
同种型:
Rabbit IgG
免疫原:
A peptide corresponding to residues near the C-terminus of human Muc17.
克隆号:
RM517
产品浓度:
N/A
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产地:
瑞士
纯度:
Protein A purified.
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