anti-NLRP3/NALP3, mAb (Cryo-2)-单抗-深圳欣博盛生物科技有限公司

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anti-NLRP3/NALP3, mAb (Cryo-2)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-20B-0014-C100

规格：100 ug

目录价：￥3960

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-NLRP3/NALP3, mAb (Cryo-2)

别名:

NACHT-, LRR- and PYD-containing Protein 3; NLRP3; Cryopyrin; Cold Autoinflammatory Syndrome 1 Protein

产品描述:

The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor family, including NLRP3/NALP3, are critical components of the inflammasome that link danger-signals to caspase-1 activation. Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS) and of chronic infantile neurologic cutaneous and articular syndrome (CINCA).

宿主来源:

Purified from concentrated hybridoma tissue culture supernatant.

实验应用:

ICC, IHC, IP, WB, CHIP

靶标/特异性:

Recognizes mouse and human NLRP3/NALP3.

同种型:

Mouse IgG2b

免疫原:

Recombinant mouse NLRP3/NALP3 (pyrin domain/aa 1-93).

克隆号:

Cryo-2