anti-PLXDC2 (mouse), mAb (Bonny-1) (25 ug)-单抗-深圳欣博盛生物科技有限公司

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anti-PLXDC2 (mouse), mAb (Bonny-1) (25 ug)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-20B-0086-TRIAL	规格：25 ug	目录价：￥1920
货号：AG-20B-0086-C100	规格：100 ug	目录价：￥4800

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-PLXDC2 (mouse), mAb (Bonny-1) (25 ug)

别名:

Plexin Domain-containing Protein 2; Tumor Endothelial Marker 7-related Protein

产品描述:

Plexin domain containing 2 (PLXDC2) is a nidogen/plexin homology transmembrane protein encoded by PLXDC2. PLXDC2 is specifically expressed on the surface of macrophages but not neutrophils, T cells or NK cells. PLXDC2 has several functions: i) in the brain, it is involved in the proliferation and differentiation of neural progenitors during the development of the nervous system; ii) in the immune system, PLXDC2 on macrophages binds to secreted PTEN (phosphatase and tensin homolog) to sequentially activate JAK2-STAT1 signaling, reprogram macrophages and drive antitumor immunity. Aberrant expression of PLXDC2 in different cancers has been reported. PLXDC2, together with its homolog PLXDC1, also seems to be the receptor for pigment epithelium-derived factor (PEDF) in endothelial cells.

宿主来源:

Purified from concentrated hybridoma tissue culture supernatant.

实验应用:

FACS

靶标/特异性:

Recognizes endogenous mouse PLXDC2.

同种型:

Mouse IgG2akappa

免疫原:

Recombinant mouse PLXDC2.

克隆号:

Bonny-1