anti-Polyglutamylation Modification, mAb (GT335) (Biotin)-单抗-深圳欣博盛生物科技有限公司

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anti-Polyglutamylation Modification, mAb (GT335) (Biotin)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-20B-0020B-C100

规格：100 ug

目录价：￥5400

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-Polyglutamylation Modification, mAb (GT335) (Biotin)

别名:

Polyglutamylated Tubulin; Glutamylated Tubulin; Postranslational Protein Glutamylation

产品描述:

Polyglutamylation is a post-translational modification in which glutamate side chains of variable lengths are formed on the modified protein. It is evolutionarily conserved and the most prominent substrate is tubulin, the microtubule (MT) building block. Polyglutamylation has been proposed to be involved in the functional adaptation of MTs, as it occurs within the carboxy-terminal tubulin tails that participate directly in the binding of many structural and motor MT-associated proteins. The recent identification of new substrates of polyglutamylation indicates that this post-translational modification could be a potential regulator of diverse cellular processes and be involved in cell cycle and cell proliferation.

宿主来源:

Purified from concentrated hybridoma tissue culture supernatant.

实验应用:

ICC, IHC, IP, WB

靶标/特异性:

Recognizes the posttranslational modification (poly)glutamylation on proteins. Reacts with polyglutamylated alpha- and beta-tubulin.

同种型:

Mouse IgG1kappa

免疫原:

Octapeptide EGEGE*EEG, modified by the addition of two glutamyl units onto the fifth E (indicated by an asterisk).

克隆号:

GT335