anti-PSD-95 (palmitoylated), mAb (rec.) (PF11) (25 ug)-单抗-深圳欣博盛生物科技有限公司

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anti-PSD-95 (palmitoylated), mAb (rec.) (PF11) (25 ug)

品牌：Adipogen

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说明书

折扣/货期

货号：AG-27B-0021-C100	规格：100 ug	目录价：￥4560
货号：AG-27B-0021-TRIAL	规格：25 ug	目录价：￥1740

产品详情

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产品名称:

anti-PSD-95 (palmitoylated), mAb (rec.) (PF11) (25 ug)

别名:

PSD95; Disks Large Homolog 4; DLG4; Postsynaptic Density Protein 95; Synapse-associated Protein 90; SAP90

产品描述:

PSD-95 is a member of proteins located at a specialized postsynaptic membrane region, called the postsynaptic density (PSD). PSD-95 is the most abundant scaffold protein specifically enriched in the PSD. It contains three PDZ domains, an SH3 domain and a guanylate kinase (GuK)-like domain. Through its PDZ domains, PSD-95 assembles various synaptic components at the PSD including intracellular signaling molecules (e.g. SynGAP and kalirin-7), ion channels (e.g. stargazin/AMPA receptors [AMPARs] and NMDA receptors) and cell adhesion molecules (e.g. neuroligin). PSD-95 plays a primary role in synaptic development and maturation and is regulated by palmitoylation at its N-terminal cysteine residues leading to its postsynaptic targeting. Palmitoylation of PSD-95 is triggered by DHHC2, a plasma membrane-inserted palmitoylating enzyme. Palmitoylated PSD-95 is almost exclusively localized at excitatory synapses in neurons.

宿主来源:

Produced without the use of animals. Purified from HEK 293 cell culture supernatant.

实验应用:

ICC, IHC

靶标/特异性:

Recognizes human, mouse and rat palmitoylated PSD-95.

同种型:

Human IgG2

免疫原:

Palmitoylated PSD-95.

克隆号:

PF11