anti-Sirtuin 6 (human), mAb (S6R82-2)-单抗-深圳欣博盛生物科技有限公司

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anti-Sirtuin 6 (human), mAb (S6R82-2)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-20A-0091-C050	规格：50 ug	目录价：￥1440
货号：AG-20A-0091-C100	规格：100 ug	目录价：￥2160

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-Sirtuin 6 (human), mAb (S6R82-2)

别名:

SIRT6; NAD-dependent Deacetylase Sirtuin-6; Mono-ADP-ribosyltransferase Sirtuin 6; SIR2-like Protein 6; SIR2L6

产品描述:

Sirtuin 6 (SIRT6) is a NAD-dependent protein deacetylase with activity towards 'Lys-9' and 'Lys-56' of histone H3. It modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. It is required for genomic stability and for normal IGF1 serum levels and normal glucose homeostasis. It also regulates cellular senescence and apoptosis. Unlike most sirtuins, SIRT6 preferentially removes long-chain fatty-acyl, rather than acetyl, protein modifications. This activity regulates secretion of the inflammation-associated protein TNF-alpha.

实验应用:

ELISA, WB

靶标/特异性:

Recognizes human sirtuin 6. Detects a band of ~47kDa by Western blot.

同种型:

Mouse IgG2bkappa

免疫原:

Recombinant human sirtuin 6.

克隆号:

S6R82-2

产品浓度:

1mg/ml