官网链接
折扣/货期| 货号：22081-1 mg | 规格：1 mg | 目录价：￥509 |
| 货号：22081-10 mg | 规格：10 mg | 目录价：￥3980 |
| 货号：22081-5 mg | 规格：5 mg | 目录价：￥2251 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
API-1
别名:
NSC 177223
产品描述:
An Akt inhibitor that reduces the level of phosphorylated Akt (IC50 = ~0.8 µM); binds Akt and blocks its translocation to the cell membrane; reduces cell proliferation in cancer cell lines, induces apoptosis, and, at a dose of 10 mg/kg/day, decreases tumor growth in a mouse xenograft model; inhibits cell growth (IC50s = 2-5 µM) and induces apoptosis in NSCLC and HNSCC cell lines; increases cleavage of caspases 8, 9, and 3; reduces c-FLIP levels through ubiquitin/proteasome-mediated degradation; synergistically induces apoptosis in combination with TRAIL/APO-2L
保存温度:
-20
运输温度:
-20
预期分子量:
337.3
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
36707-00-3
分子式:
C13H15N5O6
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