APS6-45-其他小分子化合物-深圳欣博盛生物科技有限公司

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APS6-45

品牌：Cayman

官网链接

说明书

折扣/货期

货号：38417-1 mg	规格：1 mg	目录价：￥388.6
货号：38417-10 mg	规格：10 mg	目录价：￥2639.8
货号：38417-25 mg	规格：25 mg	目录价：￥3309.8
货号：38417-5 mg	规格：5 mg	目录价：￥1514.2

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

APS6-45

产品描述:

An inhibitor of RETM918T and a derivative of sorafenib; selectively binds to RETM918T over EphA8, p38δ, JNK2, and c-Src (Kds = 28, 410, 940, 1,500, and 1,700 nM, respectively) and a panel of over 60 kinases at 10 µM, but also selectively binds to Cdk14, MAP4K4, and PTK5 (Kds = 55, 130, and 140 nM, respectively); inhibits TT cell colony formation at 30 nM; decreases tumor volume in a TT mouse xenograft model at 10 mg/kg per day; increases survival to adulthood in transgenic Drosophila expressing the lethal RetM955T mutation in a concentration-dependent manner; prevents the development of a rough-eye phenotype induced by RetM955T in transgenic Drosophila at 100 µM;

保存温度:

-20

运输温度:

-20

预期分子量:

548.385525

产品形式:

A solid

有效期:

1460

纯度:

≥98%