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折扣/货期| 货号：41110-1 mg | 规格：1 mg | 目录价：￥375 |
| 货号：41110-10 mg | 规格：10 mg | 目录价：￥2774 |
| 货号：41110-25 mg | 规格：25 mg | 目录价：￥5990 |
| 货号：41110-5 mg | 规格：5 mg | 目录价：￥1675 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
APX-115
别名:
EWHA-18278
产品描述:
An inhibitor of NOX1, NOX2, and NOX4 (Kis = 1.08, 0.57, and 0.63 µM, respectively, for the human enzymes); selective for these enzymes over xanthine oxidase and glucose oxidase (Kis = >100 µM for both); prevents RANKL-induced increases in ROS levels in primary mouse BMDMs at 10 or 20 µM; inhibits GM-CSF- and RANKL-induced primary mouse osteoclast differentiation at 1.1, 3.3, or 10 µM; increases femur bone mass density and strength and reduces femur and tibia resorption areas in OVX mice at 10 mg/kg per day; reduces plasma and urinary levels of 8-isoprostane, plasma levels of insulin, triglycerides, HDL, LDL, and creatinine, urinary levels of albumin, as well as renal fibrosis, in a db/db mouse model of diabetic nephropathy at 60 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
279.3365
产品形式:
A solid
纯度:
≥98%
CAS号:
1270084-92-8
分子式:
C17H17N3O
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