| 货号:9001589-1 mg | 规格:1 mg | 目录价:¥549.4 |
| 货号:9001589-10 mg | 规格:10 mg | 目录价:¥3926.2 |
| 货号:9001589-25 mg | 规格:25 mg | 目录价:¥8455.4 |
| 货号:9001589-5 mg | 规格:5 mg | 目录价:¥2103.8 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
APY0201
产品描述:
An inhibitor of PIKFYVE (IC50 = 5.2 nM); selectively inhibits IL-12 family inflammatory cytokine production (IC50s = 8, 99, and >10,000 nM for IL-12p70, IL-12p40, and TNF-α in stimulated human PBMCs); selective for PIKFYVE over a panel of 137 G protein-coupled receptors, enzymes, ion channels, and transporters, and other kinases only exhibiting >50% inhibition at LOK and ITPK1 at a concentration of 300 nM; inhibits Il-12p70 production ex vivo in murine plasma and reduces colonic inflammation in a mouse Il-10-/- cell transfer model of inflammatory bowel disease in a dose-dependent manner
保存温度:
-20
运输温度:
-20
预期分子量:
413.5
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
1232221-74-7
分子式:
C23H23N7O
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