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折扣/货期| 货号：V9749-100UG | 规格：100 ug | 目录价：￥6652.1 |
| 货号：V9749-20UG | 规格：20 ug | 目录价：￥3082.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
QKI Antibody / Protein Quaking
产品描述:
QKI, also known as HKQ, QK, QK3 or quaking, is a 341 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one KH domain. Expressed in the frontal cortex of the brain, QKI functions as an RNA-binding protein that plays an important role in myelinization and specifically binds to the RNA core sequence 5. Additionally, QKI regulates pre-mRNA splicing, and mRNA export and is involved in protecting and promoting the stability of select mRNAs. QKI may be methylated by PRMT1 and may also be phosphorylated at its C-terminus, an event that decreases QKI mRNA-binding affinity. Defects or deletions in the gene encoding QKI are associated with astrocytic tumors and may be involved in the pathogenesis of schizophrenia. Multiple isoforms of QKI exist due to alternative splicing events.
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, FACS, IF, WB
同种型:
Mouse IgG2c
免疫原:
Recombinant full-length human protein was used as the immunogen for the QKI antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
PCRP-QKI-2F10
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the QKI antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
产地:
美国
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