Arglabin-抑制剂-深圳欣博盛生物科技有限公司

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Arglabin

品牌：Cayman

官网链接

说明书

折扣/货期

货号：19502-1 mg	规格：1 mg	目录价：￥1005
货号：19502-10 mg	规格：10 mg	目录价：￥7290
货号：19502-5 mg	规格：5 mg	目录价：￥3926
货号：19502-500 µg	规格：500 µg	目录价：￥563

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Arglabin

产品描述:

A sesquiterpene γ-lactone; inhibits the growth of LS-180, SSC-4, HeLa, MCF-7, and HL-60 cancer cells (IC50s = 20, 10, 20, 20, and 50 µM, respectively); reduces tumor growth in an SCC-4 mouse xenograft model at 40 µg/g; reduces protein levels of NLRP3, caspase-1, IL-1β, and IL-18 induced by cholesterol crystals in LPS-primed mouse peritoneal macrophages at 50 nM; a selective inhibitor of the NLRP3 inflammasome over the NLRP1, AIM2, and NLRC4 inflammasomes when used at 50 nM; decreases plasma levels of IL-1β, oxidized LDL autoantibodies, total cholesterol, and triglycerides, and reduces the size of atherosclerotic lesions in the aorta of mice fed a high-fat diet at 2.5 ng/g

保存温度:

-20

运输温度:

-20

预期分子量:

246.3

产品形式:

A crystalline solid

纯度:

≥98%

来源:

Plant/Tanacetum parthenium