官网链接
折扣/货期| 货号：42324-10 mg | 规格：10 mg | 目录价：￥4690 |
| 货号：42324-25 mg | 规格：25 mg | 目录价：￥8803.8 |
| 货号：42324-5 mg | 规格：5 mg | 目录价：￥2934.6 |
| 货号：42324-50 mg | 规格：50 mg | 目录价：￥14673 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
ART558
产品描述:
A DNA polymerase θ inhibitor (IC50 = 7.9 nM for Polθ polymerase activity); selective for the polymerase activity of Polθ over its ATPase activity (IC50 = >12 µM); inhibits the repair of DNA double-strand breaks via TMEJ, but not NHEJ, in a reporter assay using an extrachromosomal DNA substrate at 0.1, 0.3, and 1 µM; induces synthetic lethality in RPE1 cells lacking BRCA1 and DLD-1 cells lacking BRCA2; reduces tumor growth in a 3D organoid culture model using cells derived from patients with BRCA1-low, 53BP1-low prostate cancer
保存温度:
-20
运输温度:
-20
预期分子量:
418.412409
产品形式:
A solid
纯度:
≥98%
CAS号:
2603528-97-6
分子式:
C21H21F3N4O2
促销活动
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