深圳欣博盛生物科技有限公司

产品货号

BP0117

产品规格

5/25/50/100mg

反应种属

Mouse

克隆号

YTS 169.4

同种型

Rat IgG2b, κ

免疫原

CBA mouse   thymocytes

实验应用

in   vivo CD8+ T cell depletion
  Western blot

产品形式

PBS, pH   7.0,Contains no stabilizers or preservatives

纯度

>95%,   Determined by SDS-PAGE

聚合

<5%,   Determined by SEC

无菌处理

0.2 µm   filtration

纯化方式

Protein G

RRID

AB_10950145

分子量

150 kDa

小鼠病原检测

Ectromelia/Mousepox   Virus: Negative

Hantavirus:   Negative

K Virus:   Negative

Lactate   Dehydrogenase-Elevating Virus: Negative

Lymphocytic Choriomeningitis   virus: Negative

Mouse   Adenovirus: Negative

Mouse   Cytomegalovirus: Negative

Mouse   Hepatitis Virus: Negative

Mouse Minute   Virus: Negative

Mouse   Norovirus: Negative

Mouse   Parvovirus: Negative

Mouse   Rotavirus: Negative

Mycoplasma Pulmonis:   Negative

Pneumonia   Virus of Mice: Negative

Polyoma   Virus: Negative

Reovirus   Screen: Negative

Sendai   Virus: Negative

Theiler’s   Murine Encephalomyelitis: Negative

保存条件

抗体原液保存在4°C，不能冷冻保存。

推荐同型对照

InVivoPlus   rat IgG2b isotype control, anti-keyhole limpet hemocyanin（货号BP0090）

推荐抗体稀释液

InVivoPure   pH 7.0 Dilution Buffer（货号IP0070）

体内CD8+T细胞耗竭

(in vivo   CD8+ T cell depletion)

1. Vashist,   N., et al. (2018). 'Influenza-Activated ILC1s Contribute to Antiviral   Immunity Partially Influenced by Differential GITR Expression' Front Immunol   9: 505.

2. Triplett,   T. A., et al. (2018). 'Reversal of indoleamine 2,3-dioxygenase-mediated   cancer immune suppression by systemic kynurenine depletion with a therapeutic   enzyme' Nat Biotechnol 36(8): 758-764.

3. Carmi,   Y., et al. (2015). 'Allogeneic IgG combined with dendritic cell stimuli   induce antitumour T-cell immunity' Nature 521(7550): 99-104.

4. Burrack,   K. S., et al. (2015). 'Myeloid Cell Arg1 Inhibits Control of Arthritogenic   Alphavirus Infection by Suppressing Antiviral T Cells' PLoS Pathog 11(10):   e1005191.

5. Wensveen,   F. M., et al. (2015). 'NK cells link obesity-induced adipose stress to   inflammation and insulin resistance' Nat Immunol 16(4): 376-385.

6. Li,   Z., et al. (2015). 'Pre-treatment of allogeneic bone marrow recipients with   the CXCR4 antagonist AMD3100 transiently enhances hematopoietic chimerism   without promoting donor-specific skin allograft tolerance' Transpl Immunol   33(2): 125-129.